Computational and analytical support for complex biological research.
Scilytica is an independent computational biology company supporting research teams through analytical services, applied research, and scientific software development. We design, evaluate, and develop computational approaches in relation to the study design, available data, and assumptions behind the methods. Analyses are implemented in reproducible software and documented workflows.
Current work focuses on single-cell, spatial, and multi-omics research.
Research
Understanding how computational methods behave across datasets, assays, and study designs.
TN-003 reports an evaluation of a locked kidney reference applied to independent Xenium samples. It documents the mapping procedure, comparison with a simpler locked method, and cell types that need further investigation.
ANA-018 is examining a related question across CosMx and Xenium, using separate measurement models and a shared single-nucleus RNA-seq reference and label ontology.
TN-003 is published. Study design and validation for ANA-018 are in progress.
Analytical services
Analysis, methods, and reproducible workflows for biological research.
Analytical support
Focused computational analysis for biological research, including single-cell, spatial, and multi-omics studies.
→02Computational method development
Development or adaptation of computational approaches for specialized biological and analytical questions.
→03Method evaluation and benchmarking
Controlled comparisons to understand how computational methods behave and where they succeed or fail.
→04Reproducible analysis workflows
Traceable implementations that research teams can review, maintain, and extend.
→05Performance and research infrastructure
Practical improvements when scale, cost, or reliability constrain the analysis.
→06Research planning and grant proposal support
Scientific and computational contributions to study plans and collaborative grant proposals.
→Methods and software
Tools developed from recurring analytical work.
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